Table A1.

Quality appraisal of studies included in the literature review.

Quality check item	Ruff (21)	Garcia-Altes et al. (27)	Varney and Guest (26)	Fenoglio et al. (25)	Rasmussen et al. (24)	Neubauer et al. (20)	Konnopk and König (18)	Rehm et al. (23)	Jarl et al. (28)	Konnopka et al. (33)	Hansen et al. (29)	Wacker et al. (22)
Clear definition of the illness?	x	x	x	x	x	x	x	x	x	x	x	x
Epidemiological sources carefully described?	x	x	x	x	x	x	x	x	x	x	x	x
Costs sufficiently disaggregated?	x	x	x	x		x	x	x	x	x	x	x
Activity data sources carefully described?	x	x	x	x	x	x	x	x	x	x	x	x
Activity data appropriately assessed?			x				x			x		x
Sources of all cost values analytically described?		x	x	x	x	x	x	x	x	x	x	x
Methods carefully explained?		x	x	x		x	x	x	x	x	x
Costs discounted?	x					x	x	x	x	x		x
Major assumptions tested in a sensitivity analysis?			x		x	x	x	x	x	x		x
Presentation of results consistent with methodology?	x	x	x	x	x	x	x	x	x	x	x	x