Fig. 5.

a Bioluminescence imaging of a representative mouse injected with MDA-ctr (control) cells or with MDA-miR cells. All the images are scaled with the same color bar. b Graphical representation of average of Luciferase activity acquired for each of the tumor formed by MDA-ctr (ctr) and MDA-miR (miR) cell lines, respectively, at different time points (day 3, 7, 10, 17, 22). Data are presented as average radiance (photons/s/cm²/steradian). All the bars are mean ± SEM of experiments for each cell line at each time point (**t test p value day 7 = 0.008; *t test p value day 17 = 0.015;** t test p value day 22 = 0.007, n = 14). c Graphical representation of average of volume for each of the tumor formed by MDA-ctr (ctr) and MDA-miR (miR) cell lines, respectively, at each time point (day 3 7, 10, 17, 22). All the bars are mean ± SEM of experiments for each cell line at each time point (*t test p value day 3 = 0.025; **t test p value day 7 = 0.010; **t test p value day 17 = 0.006; **t test p value day 22 = 0.002, n = 14). d Representative image of the difference in the volume of explanted tumors, generated by MDA-ctr (left) and MDA-miR (right) cells, respectively