Table 3.
Amino-acid handling by abdominal organs (n = 20)
| Arterial venous differences (µmol/L) | Splanchnic area | PDV | Liver | Small intestine | Colon | Spleen | Kidneys |
|---|---|---|---|---|---|---|---|
| Glutamate | −66.4 (13.1)* | 2.4 (3.6) | −74.0 (13.1)* | −5.0 (4.2) | 6.8 (2.8) | 12.4 (3.2) | −1.5 (3.2) |
| Asparagine | 4.7 (1.3) | −4.4 (1.3)* | 8.4 (1.8)* | −4.0 (1.5)* | −0.2 (1.1) | −3.0 (2.2) | −5.5 (0.8) |
| Serine | 4.6 (2.8) | 0.6 (1.7) | 4.6 (2.8) | −5.0 (5.3) | 4.3 (1.8) | 2.6 (1.8) | −58.0 (4.4)* |
| Glutamine | 29.3 (7.3) | 42.1 (8.7)* | 1.3 (6.2) | 121.0 (23.8)* | 20.8 (13.3) | 14.3 (10.5) | 22.2 (17.5) |
| Histidine | 3.1 (1.5) | −3.2 (1.2) | 6.0 (1.5)* | −5.0 (2.2) | −2.6 (2.6) | −4.2 (2.4) | −5.9 (1.8) |
| Glycine | −24.0 (15.8) | −14.8 (20.9)* | −14.2 (13.4) | −57.9 (22.4)* | −10.8 (17.2) | −15.5 (20.6) | −0.8 (20.2) |
| Threonine | 0.6 (3.0) | −3.4 (1.8) | 3.2 (3.2) | −7.0 (3.3) | 2.0 (2.7) | −1.1 (3.1) | −5.7 (3.2) |
| Citrulline | −5.4 (1.1) | −14.5 (2.1)* | 4.8 (1.6)* | −36.1 (4.6)* | −2.4 (3.1) | −0.8 (1.1) | 17.3 (2.0) |
| Arginine | 16.5 (3.9) | −8.1 (2.1)* | 21.8 (4.7)* | −17.7 (4.5)* | −0.8 (2.2) | −0.3 (2.3) | −14.6 (2.4) |
| Alanine | 54.2 (11.9) | −47.1 (5.3)* | 86.3 (12.5)* | −79.0 (10.1)* | −36.7 (4.6)* | −20.8 (6.1) | −61.8 (5.2)* |
| Taurine | −3.0 (3.5) | −6.3 (2.5) | 1.8 (3.7) | −3.4 (2.7) | −7.4 (2.7) | −9.6 (3.3)* | 8.3 (4.9) |
| aab | 0.1 (0.6) | 0.4 (0.5) | −0.2 (0.6) | −0.2 (0.4) | 0.2 (0.5) | 0.5 (0.6) | −1.7 (0.4) |
| Tyrosine | 7.8 (1.8)* | 2.2 (2.2) | 6.8 (1.7)* | −2.7 (2.3) | 0.0 (1.5) | 0.5 (2.8) | −12.0 (1.3)* |
| Valine | 1.3 (3.8) | −1.8 (2.9) | 3.1 (3.3) | −9.7 (4.5) | 1.8 (3.1) | −2.0 (5.1) | 4.3 (5.2) |
| Methionine | 4.9 (1.2)* | −0.8 (1.0) | 5.9 (1.1)* | −3.7 (1.8) | 0.9 (1.4) | 0.5 (1.5) | 5.4 (1.9) |
| Isoleucine | 1.8 (1.5) | −0.8 (1.5) | 2.2 (1.5) | −3.3 (1.8) | −0.6 (1.7) | 3.9 (2.2) | 1.5 (3.2) |
| Phenylalanine | 2.7 (1.0) | −2.8 (1.1) | 5.0 (1.0)* | −4.0 (1.8) | −2.2 (1.1) | −2.5 (1.9) | 0.5 (1.9) |
| Tryptophan | 1.4 (0.7) | 1.0 (0.8) | 0.7 (0.5) | −0.3 (0.9) | 1.6 (1.5) | 2.9 (1.2) | 3.2 (1.6) |
| Leucine | 1.2 (2.3) | −6.6 (1.8)* | 6.2 (2.4)* | −8.2 (3.6) | −2.1 (2.0) | −6.7 (2.9) | −13.1 (2.1) |
| Ornithine | −12.4 (3.5) | 3.0 (1.3) | −14.9 (3.8)* | 5.6 (3.4) | 1.2 (2.6) | −3.4 (3.5) | −14.1 (5.7) |
| Lysine | 3.5 (8.6) | −20.1 (7.7)* | 18.3 (5.1)* | −20.9 (9.1) | −14.1 (9.3) | −10.3 (8.7) | −30.3 (10.0) |
Results are presented as means (SEM)
Positive arterial venous differences indicate net amino-acid uptake, negative arterial venous differences indicate net release
* P values below 0.05 were considered statistically significant