Table 1. The distributions of the selected variables in the CAD cases and controls.
Variable | CAD (n = 435) | Controls (n = 480) | p |
Mean age, y | 61.30 (±9.71) | 60.79 (±7.54) | 0.38 |
Woman, % | 155 (35.6) | 184 (38.3) | 0.40 |
Mean BMI, kg/m2 | 25.99 (±3.28) | 26.24 (±2.75) | 0.22 |
Family history of CAD, % | 98 (22.5) | 63 (13.1) | < 0.001 |
Previous smoker, % | 247 (56.8) | 211 (44.0) | < 0.001 |
Previous drinker, % | 82 (18.9) | 81 (16.9) | 0.44 |
Hypertension, % | 305 (70.1) | 297 (61.9) | 0.009 |
Hyperlipidemia, % | 274 (63.0) | 286 (59.6) | 0.29 |
Diabetes mellitus, % | 113 (26.0) | 90 (18.8) | 0.009 |
Previous stroke, % | 22 (5.1) | 11 (2.3) | 0.03 |
Previous myocardial infarction, % | 100 (23.0) | — | — |
Previous percutaneous coronary intervention, % | 221 (50.8) | — | — |
Previous coronary artery bypass grafting, % | 41 (9.4) | — | — |
Fasting blood glucose (mmol/l) | 5.92 (±2.25) | 5.41 (±1.07) | < 0.001 |
Uric acid (μmol/l) | 325.82 (±85.40) | 312.60 (±79.60) | 0.02 |
Creatinine (μmol/l) | 68.69 (±18.02) | 62.84 (±21.45) | < 0.001 |
Total cholesterol (mmol/l) | 4.70 (±1.07) | 4.86 (±2.85) | 0.28 |
Triglyceride (mmol/l) | 1.89 (±1.67) | 1.64 (±0.95) | 0.006 |
High density lipoprotein (mmol/l) | 1.03 (±0.24) | 1.16 (±0.33) | < 0.001 |
Low density lipoprotein (mmol/l) | 3.02 (±0.93) | 3.07 (±0.83) | 0.40 |
Fibrinogen (g/l) | 2.74 (±0.64) | 2.61 (±0.62) | 0.002 |
Aspirin, % | 427 (98.2) | 414 (88.5) | < 0.001 |
Clopidogrel, % | 312 (71.7) | 15 (3.2) | < 0.001 |
Nitroglycerin, % | 350 (80.6) | 61 (13.0) | < 0.001 |
Angiotensin converting enzyme inhibitor, % | 148 (34.1) | 126 (27.0) | 0.02 |
Angiotensin II receptor blockers, % | 97 (22.4) | 74 (15.8) | 0.01 |
β-blocker, % | 333 (76.6) | 230 (49.1) | < 0.001 |
Ca2+ antagonist, % | 171 (39.4) | 156 (33.3) | 0.06 |
Statins, % | 418 (96.1) | 310 (66.2) | < 0.001 |
Diuretics, % | 41 (9.5) | 21 (4.5) | 0.003 |
Insulin, % | 37 (8.5) | 10 (2.1) | < 0.001 |
Oral hypoglycemic drugs, % | 102 (23.5) | 55 (11.8) | < 0.001 |
BMI, body mass index; CAD, coronary artery disease; Ca2+, calcium channels. Bold values are statistically significant (p < 0.05); The medical information was available in 433-435 CAD cases and 465-468 non-CAD controls.