Table 1.
Variable | No recurrence (n = 220) | Recurrence (n = 34) | P | ||
---|---|---|---|---|---|
N | % | N | % | ||
MRE11 positive cells | 0.030 | ||||
≤50% | 73 | 33.18 | 5 | 14.71 | |
>50% | 147 | 66.82 | 29 | 85.29 | |
Stage | <0.001 | ||||
I | 88 | 40.00 | 2 | 5.88 | |
II, III | 132 | 60.00 | 32 | 94.12 | |
Grade | 0.543 | ||||
1, 2 | 166 | 75.45 | 24 | 70.59 | |
3 | 54 | 24.55 | 10 | 29.41 | |
Age | 0.007 | ||||
<52 yrs | 126 | 57.27 | 11 | 32.35 | |
≥52 yrs | 94 | 42.73 | 23 | 67.65 | |
BMI (kg/m2) | 0.151 | ||||
<24 | 126 | 57.27 | 15 | 44.12 | |
≥24 | 94 | 42.73 | 19 | 55.88 | |
Tumor size (cm) | <0.001 | ||||
<2.4 cm | 150 | 68.18 | 11 | 32.35 | |
≥2.4 cm | 70 | 31.82 | 23 | 67.65 | |
LN metastasis | 0.003 | ||||
Negative | 149 | 67.73 | 14 | 41.18 | |
Positive | 71 | 32.27 | 20 | 58.82 | |
ER | <0.001 | ||||
Negative | 63 | 28.64 | 20 | 58.82 | |
Positive | 157 | 71.36 | 14 | 41.18 | |
PR | 0.009 | ||||
Negative | 90 | 40.91 | 22 | 64.71 | |
Positive | 130 | 59.09 | 12 | 35.29 | |
HER2 status | 0.430 | ||||
Negative | 140 | 63.64 | 24 | 70.59 | |
Positive | 80 | 36.36 | 10 | 29.41 | |
Triple negative | 0.002 | ||||
No | 190 | 86.36 | 22 | 64.71 | |
Yes | 30 | 13.64 | 12 | 35.29 | |
RT | 0.021 | ||||
No | 91 | 41.36 | 7 | 20.59 | |
Yes | 129 | 58.64 | 27 | 79.41 | |
CT | 0.866 | ||||
No | 30 | 13.64 | 5 | 14.71 | |
Yes | 190 | 86.36 | 29 | 85.29 | |
HT | 0.001 | ||||
No | 72 | 32.73 | 21 | 61.76 | |
Yes | 148 | 67.27 | 13 | 38.24 |
∗1Dataset was retrieved from our previous study [9]. MRE11: meiotic recombination 11; BMI: body mass index; LN: lymph node; ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2; RT: radiotherapy; CT: chemotherapy; HT: hormone therapy.