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Simplified mechanisms of inflammation signaling caused by adverse drug reactions (ADRs) in the liver. Abbreviations are used as follows: toll-like receptor (TLR), major histocompatibility complex (MHC), T cell receptor (TCR), drug metabolizing enzymes (DMEs), antigen-presenting cell (APC), cytotoxic T lymphocyte (TC cell), and helper T lymphocyte (TH cell).
