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Randomized Phase III trials in advanced hepatocellular carcinoma
| Drug | n (patients) | OS (mo) | HR |
| SOR/Exp arm | |||
| First line completed (Sorafenib standard) | |||
| Brivanib | 1155 | 9.9/9.5 | 1.06 |
| Sunitinib | 1074 | 10.2/7.9 | 1.3 |
| Sorafenib/Erlotinib | 720 | 8.5/9.5 | 0.92 |
| Linifanib | 1035 | 9.8/9.1 | 1.04 |
| Second line completed (placebo standard) | |||
| Brivanib | 395 | 8.2/9.4 | 0.89 |
| Everolimus | 546 | 7.3/7.6 | 1.05 |
| Ramucirumab | 565 | 7.6/9.2 | 0.86 |
OS: Overall survival; SOR: Sorafenib arm.
