Figure 2.

Increased terminal glycosylation of the TREM2 R47H variant in the trans-Golgi. (A) After monensin (10 μM) treatment for 8 h, the highest bands (a) for wild type TREM2 and the R47H variant were decreased in intensity, whereas the middle bands (b) were increased. (B) After kifunensin (2 μg/μl) treatment for 4 h, the intensity of the highest bands (a) for wild type TREM2 and the R47H variant were decreased. These data represent the mean ± S.E. from three independent experiments. ^*P < 0.05, ^**P < 0.01.