Table 1.
SI (mean + SD) | |||||
Variables | No. of cases | Ki-67 | Cyclin DI | Cyclin A | Histone H3 |
Sex | |||||
Male | 36 | 18.0 ± 6.4 | 6.7 ± 4.3 | 12.7 ± 5.7 | 10.7 ± 5.3 |
Female | 24 | 20.1 ± 5.8 | 8.8 ± 8.4 | 10.0 ± 6.0 | 10.7 ± 5.4 |
Age (years) | |||||
≥50 | 41 | 11.7 ± 6.0* | 5.6 ± 5.2 | 10.0 ± 5.3 | 6.0 ± 5.0* |
<50 | 19 | 23.8 ± 5.6 | 7.7 ± 6.8 | 13.6 ± 5.7 | 22.0 ± 5.2 |
Tumor size (cm) | |||||
<5.0 | 33 | 12.2 ± 6.3* | 5.3 ± 3.8* | 11.5 ± 6.1* | 10.3 ± 4.9* |
≥5.0 | 27 | 30.1 ± 6.2 | 22.8 ± 7.2 | 28.6 ± 5.6 | 24.0 ± 5.6 |
Histology | |||||
Normal | 20 | 3.5 ± 2.0* | 0.6 ± 0.2* | 2.3 ± 1.1* | 2.2 ± 0.9 |
Carcinoma | 60 | 30.3 ± 6.2 | 24.9 ± 6.3 | 27.2 ± 5.8 | 10.7 ± 5.3 |
GI | 15 | 11.7 ± 6.2 | 6.6 ± 4.0 | 10.0 ± 5.4 | 11.4 ± 4.9 |
GII | 21 | 11.8 ± 5.6 | 8.9 ± 3.6 | 12.3 ± 6.5 | 7.8 ± 5.4 |
GIII | 24 | 30.0 ± 4.3 | 22.0 ± 8.1 | 27.0 ± 4.9 | 11.5 ± 5.4 |
Lymph node | |||||
Negative | 33 | 19.5 ± 7.0 | 5.4 ± 5.3* | 11.9 ± 6.5 | 12.3 ± 5.5 |
Positive | 27 | 21.3 ± 4.9 | 20.6 ± 6.9 | 12.5 ± 5.0 | 14.2 ± 5.0 |
Depth of invasion | |||||
m, sm | 17 | 20.7 ± 6.7 | 3.1 ± 3.1* | 11.9 ± 7.2 | 10.4 ± 5.1 |
beyond sm | 43 | 21.9 ± 6.2 | 12.4 ± 6.5 | 12.2 ± 5.6 | 10.7 ± 5.4 |
Stage | |||||
I | 6 | 20.6 ± 6.7 | 5.7 ± 6.9 | 24.2 ± 6.9 | 11.1 ± 5.3 |
II | 27 | 20.8 ± 6.9 | 5.3 ± 4.3 | 24.6 ± 6.0 | 10.4 ± 5.7 |
III | 12 | 22.0 ± 5.4 | 7.7 ± 6.0 | 27.1 ± 5.2 | 10.4 ± 4.9 |
IV | 15 | 24.7 ± 6.1 | 11.3 ± 9.6 | 27.5 ± 5.5 | 12.3 ± 6.2 |
* p. value < 0.05 (significant)