Table 2.

The relation between cyclin D1 overexpression vs cyclin D1 amplification and clinicopathological prognostic markers.

Variables	No. of cases	Cyclin DI overexpression	Cyclin D1 Amplification
Tumor size (cm)
<5.0	33	5.3 ± 3.8*	13/33
≥5.0	27	22.8 ± 7.2 p <0.05	9/27 p <0.236
Histology
GI	15	6.6 ± 4.0	7/15
GII	21	8.9 ± 3.6	8/21
GIII	24	22.0 ± 8.1 p <0.001	7/24 p <0.075
Lymph node
Negative	33	5.4 ± 5.3*	6/33 (18.2%)
Positive	27	20.6 ± 6.9 p <0.05	16/27 (59.3%) p <0.008
Depth of invasion
m, sm	17	3.1 ± 3.1*	4/17 (23.5%)
beyond sm	43	12.4 ± 6.5 p <0.05	26/43 (60.5%) p <0.001
Stage
early	45	5.5 ± 10.1	12/45 (26.7%)
late	15	11.3 ± 9.6 P = 0.175	10/15 (66.7%) p <0.002