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. 2017 Jan 18;7:40787. doi: 10.1038/srep40787

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(a) Aβ monomer (30 μM) seeded with 6 μM of either iLFAOs (●) or pLFAOs (○). (b) pLFAOs (10 μM) seeded with 2 μM of either iLFAOs (●) or pLFAOs (○). For both a and b, kinetic measurements were taken every 30 s beginning immediately after the addition of 10 μM ThT. (c) Numerical simulations of sLFAO aggregate formation (●, Fig. 3a), along with (d) R² values for each respectively LFAO assembly (gateway) considered.