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. 2016 Oct 19;30(1):61–72. doi: 10.1021/acs.chemrestox.6b00285

Table 1. Mutation Frequency of dG-N2-IQ (in Three Different Guanines of the NarI Site), dG-N2-MC, and dG-N2-2,7-DAM and Their Change in Percentages upon Knockdown of Specific Pols.

lesion MF (%) % change in MF in pol η-deficient cells % change in MF in pol κ-deficient cells % change in MF in pol ι-deficient cells % change in MF in pol ζ-deficient cells % change in MF in Rev1-deficient cells % change in MF in (η, ζ, Rev1) deficient cells
dG1-N2-IQ 22.7 –21 +23 –12 –16 –20 –84
dG2-N2-IQ 17 –21 +18 –18 –18 –21 –87
dG3-N2-IQ 11 –27 +5 –15 –18 –22 –90
dG-N2-MC 18 –44 +39 NDa –33 ND –78
dG-N2-2,7-DAM 10 –20 +50 ND –10 ND –81
a

ND, not determined.