Table 1. Mutation Frequency of dG-N2-IQ (in Three Different Guanines of the NarI Site), dG-N2-MC, and dG-N2-2,7-DAM and Their Change in Percentages upon Knockdown of Specific Pols.
lesion | MF (%) | % change in MF in pol η-deficient cells | % change in MF in pol κ-deficient cells | % change in MF in pol ι-deficient cells | % change in MF in pol ζ-deficient cells | % change in MF in Rev1-deficient cells | % change in MF in (η, ζ, Rev1) deficient cells |
---|---|---|---|---|---|---|---|
dG1-N2-IQ | 22.7 | –21 | +23 | –12 | –16 | –20 | –84 |
dG2-N2-IQ | 17 | –21 | +18 | –18 | –18 | –21 | –87 |
dG3-N2-IQ | 11 | –27 | +5 | –15 | –18 | –22 | –90 |
dG-N2-MC | 18 | –44 | +39 | NDa | –33 | ND | –78 |
dG-N2-2,7-DAM | 10 | –20 | +50 | ND | –10 | ND | –81 |
ND, not determined.