Fig. 1.

The DGC, UGC and α7-integrin are not requisite for binding of GalNAc-specific lectins. Transverse 8-µm serial cryosections of murine quadriceps muscles from 12-week-old wild-type, mdx, utrophin-null (Utr^−/−) and alpha-7-integrin-null (α7^−/−) mice were stained with hematoxylin and eosin (H&E, top row), anti-utrophin antibody (bottom row), and the following biotinylated reagents: WFA, VVA, SBA and DBA. Bound lectins and antibodies were detected with FITC-avidin D (green) and counterstained with Texas Red conjugated alpha-bungarotoxin (red). Merged images are depicted. Insets depict neuromuscular junctions. Scale bar is 50 µm. This figure is available in black and white in print and in color at Glycobiology online.