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Effect of amino acid mutations in peptide P2 on parasite growth inhibition. A, parasite culture at late schizont stage was incubated with 20 μm wild type P2 or its mutated peptides or PBS alone. After 40 h, parasitemia was determined by ethidium bromide staining and measured by flow cytometry. B, scatter plot was drawn to see the pattern of relationship between parasite growth and basigin-binding affinity of mutant P2 peptides.
