FIGURE 7.

Small angle X-ray scattering analysis of EGFR CTT. A, scattering profiles of EGFR CTT (red) and BSA (blue). B, Guinier plots of EGFR CTT in different concentrations (0.9, 1.8, and 3.7 mg ml⁻¹). C, the data are represented in a Kratky plot with arbitrary units. In folded proteins like BSA (blue), the Kratky plot shows parabolic features, whereas in the EGFR CTT Kratky plot (red), a hyperbolic shape indicates intrinsically disordered protein character. D, pair distribution functions for the EGFR CTT (red) and BSA (blue) scattering profiles generated using Datgnom (52).