FIGURE 3.

AUC analysis of BCAP splice variant and N-terminal variant. A and B, sedimentation velocity profiles, residuals, and sedimentation coefficient distribution, c(S), for the splice variant BCAP_S, which lacks the first 180 amino acids and contains the DBB domain and ANK repeats (residues 322–403) (A), and BCAP₃₃₀, which consists of the N-terminal 330 residues and includes the putative TIR and DBB domains (B). Both are dimeric, revealing that the DBB and ANK domains are responsible for BCAP_L self-association. Every third scan is shown for clarity.