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. 2017 Jan 18;7:40958. doi: 10.1038/srep40958

Figure 8. Proposed mechanism of pulmonary fibrosis induced by upregulated miR-497-5p.

Figure 8

miR-497-5p targets Reck, which leads to myofibroblast differentiation of lung resident mesenchymal stem cells and pulmonary fibrosis through activating latent TGF-β1.