Table 1. . Patients’ characteristics in a discovery set.
| Characteristic | Short OS (n = 15) | Long OS (n = 15) |
Hazard ratio 95% CI |
p-value† | |
|---|---|---|---|---|---|
| Lower | Upper | ||||
| Age (years): | |||||
| – Mean (range) |
58 (25–67) |
46 (20–75) |
0.07 |
2.76 |
0.36 |
| Gender: | |||||
| – Male (%) |
9 (60) |
11 (73) |
0.35 |
3.88 |
0.93 |
| KPS: | |||||
| – Mean (range) |
75 (45–95) |
80 (55–100) |
0.005 |
0.50 |
0.009* |
| Surgical treatment (%) |
13 (87) |
15 (100) |
0.15 |
11.7 |
0.90 |
| Chemotherapy, n (%) |
14 (93) |
11 (73) |
1.26 |
26.5 |
0.021* |
| RT before vaccination (Gy): | |||||
| – Average (SD) | 67 (22.3) | 61 (8.7) | 0.03 | 13.3 | 0.96 |
†Cox proportional hazard regression with the OS from vaccination started as the time variable was used.
*Statistical significance (p < 0.05).
KPS: Karnovski performance status; OS: Overall survival; RT: Radio therapy (total absorbed dose); SD: Standard deviation.