Fig. 2.

Kinetic of fecal multidrug resistant P. aeruginosa loads in human microbiota-associated mice with and without acute ileitis. Human microbiota-associated mice were perorally challenged with T. gondii ME49 to induce acute ileitis (ILE; filled circles) and additionally infected with MDR P. aeruginosa 3 days following ileitis induction. P. aeruginosa infected human microbiota-associated mice without ileitis induction (N; open circles) served as controls. Intestinal colonization densities were determined in fecal samples at days (d) 2, 3 and 4 following P. aeruginosa infection by culture and expressed as colony forming units per gram feces (CFU/g). Numbers of mice harboring P. aeruginosa out of the total number of analyzed mice are given in parentheses. Medians (black bars) and significance levels (p values) determined by Kruskal–Wallis test are indicated. Data shown were pooled from three independent experiments