Table 2.
Over- and under-represented sperm-free SF-induced differentially expressed genes (P < 0.05) in the GO- biological process involving immune system function in chicken
| GO-BP (immune function) | REF | DE (721) | EXPC | FE(+/−) | P value |
|---|---|---|---|---|---|
| Positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation (GO:2000454) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation (GO:2000452) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Positive regulation of CD8-positive, alpha-beta T cell extravasation (GO:2000451) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Regulation of CD8-positive, alpha-beta T cell extravasation (GO:2000449) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Positive regulation of interleukin-15 production (GO:0032738) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Positive regulation of T cell extravasation (GO:2000409) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Regulation of T cell extravasation (GO:2000407) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Regulation of interleukin-15 production (GO:0032658) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Positive regulation of neutrophil apoptotic process (GO:0033031) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Positive regulation of isotype switching to IgA isotypes (GO:0048298) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| T-helper 2 cell cytokine production (GO:0035745) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| TIRAP-dependent toll-like receptor 4 signaling pathway (GO:0035665) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| TIRAP-dependent toll-like receptor signaling pathway (GO:0035664) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Positive regulation of establishment of T cell polarity (GO:1903905) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Interleukin-8 biosynthetic process (GO:0042228) | 1 | 1 | 0.05 | +21.9 | 4.46E-02 |
| Negative regulation of macrophage chemotaxis (GO:0010760) | 4 | 2 | 0.18 | +10.95 | 1.48E-02 |
| Positive regulation of macrophage chemotaxis (GO:0010759) | 5 | 2 | 0.23 | +8.76 | 2.24E-02 |
| Regulation of macrophage chemotaxis (GO:0010758) | 11 | 4 | 0.5 | +7.96 | 1.77E-03 |
| Negative regulation of leukocyte chemotaxis (GO:0002689) | 9 | 3 | 0.41 | +7.3 | 8.50E-03 |
| Positive regulation of macrophage differentiation (GO:0045651) | 10 | 3 | 0.46 | +6.57 | 1.13E-02 |
| Regulation of macrophage differentiation (GO:0045649) | 14 | 4 | 0.64 | +6.26 | 4.17E-03 |
| Negative regulation of alpha-beta T cell activation (GO:0046636) | 12 | 3 | 0.55 | +5.47 | 1.82E-02 |
| Lymphocyte chemotaxis (GO:0048247) | 14 | 3 | 0.64 | +4.69 | 2.71E-02 |
| Monocyte chemotaxis (GO:0002548) | 16 | 3 | 0.73 | +4.11 | 3.79E-02 |
| Negative regulation of response to cytokine stimulus (GO:0060761) | 27 | 4 | 1.23 | +3.24 | 3.66E-02 |
| Positive regulation of T cell proliferation (GO:0042102) | 52 | 6 | 2.37 | +2.53 | 3.39E-02 |
| Regulation of leukocyte chemotaxis (GO:0002688) | 57 | 6 | 2.6 | +2.31 | 4.89E-02 |
| Regulation of leukocyte migration (GO:0002685) | 85 | 8 | 3.88 | +2.06 | 4.39E-02 |
REF, Gallus gallus reference gene list (15789); DE, mating-induced differentially expressed genes (P < 0.05) in the UVJ; EXPC, expected number of genes in DE genes; FE, fold enrichment