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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Behav Brain Res. 2016 Nov 24;320:302–315. doi: 10.1016/j.bbr.2016.11.024

Figure 4.

Figure 4

There were no differences between STs (n = 21) and GTs (n = 24) in the acquisition of cocaine acquisition in Experiment 1 as indicated by similar (A) number of active and inactive responses, and (B) number of cocaine infusion/min for infusion criteria 5 and 10 (0.4 mg/kg/inf) and 20 and 40 (0.2 mg/kg/inf). Paired groups demonstrated greater cue-induced reinstatement (rein) of drug-seeking behavior than Unpaired groups using a classically conditioned auditory cue as indicated by number of active responses made during the cue-induced reinstatement test compared to final day of extinction (ST-UP, n = 10; ST-P, n = 11; GT-UP, n = 12; GT-P, n = 12).* indicates significant difference from unpaired group within phenotype during reinstatement; # indicates significant difference between reinstatement test and extinction within group. Values represent means ± SEM.