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. Author manuscript; available in PMC: 2017 Jan 18.
Published in final edited form as: Ann Intern Med. 2013 Nov 5;159(9):592–600. doi: 10.7326/0003-4819-159-9-201311050-00005

Table 3.

Deaths and Mortality Rates for Substance-Related Deaths After Release, Overall and by Sex*

Substance Involved Overall (n = 76 208)
Men (n = 63 979)
Women (n = 12 229)
Deaths, n Deaths per 100 000 Person-Years (95% CI) Deaths, n Deaths per 100 000 Person-Years (95% CI) Deaths, n Deaths per 100 000 Person-Years (95% CI)
Opioids 365 109 (98–120) 283 100 (89–112) 82 158 (124–193)

 Pharmaceutical opioids 259 77 (68–87) 189 67 (57–76) 70 135 (104–167)

 Methadone 176 53 (45–60) 130 46 (38–54) 46 89 (63–115)

 Heroin 123 37 (30–43) 107 38 (31–45) 16 31 (16–46)

Cocaine 209 63 (54–71) 157 56 (47–64) 52 100 (73–128)

Other and unspecified narcotics 184 55 (47–63) 142 50 (42–59) 42 81 (57–106)

Psychostimulants 136 41 (34–48) 109 39 (31–46) 27 52 (32–72)

Alcohol 93 28 (22–33) 77 27 (21–33) 16 31 (16–46)

Antidepressants 103 31 (25–37) 65 23 (17–29) 38 73 (50–97)

Benzodiazepines 60 18 (13–22) 43 15 (11–20) 17 33 (17–48)

Neuroleptics 26 8 (5–11) 20 7 (4–10) 6 12 (4–25)

Barbiturates 4 1 (0–3) 3 1 (0–3) 1 2 (0–11)

Cannabis 2 1 (0–2) 2 1 (0–3) 0 0 (0–7)

Other psychotropics 2 1 (0–2) 2 1 (0–3) 0 0 (0–7)
*

Overdose may not be listed as the underlying cause of death for the deaths listed. For example, of the 259 deaths where pharmaceutical opioids were involved, 33 (12.7%) listed an underlying cause other than overdose.

Not mutually exclusive as each substance may be listed more than once among the multiple cause-of-death listings per individual.