Skip to main content
. Author manuscript; available in PMC: 2017 Jan 18.
Published in final edited form as: Ann Intern Med. 2013 Nov 5;159(9):592–600. doi: 10.7326/0003-4819-159-9-201311050-00005

Table 4.

Most Common Substance Combinations Listed in Substance-Related Deaths and Associated Mortality Rates

Combination Deaths, n Deaths per 100 000 Person-Years (95% CI)
Opioid and cocaine 37 11 (8–15)
Cocaine and other narcotics 36 11 (7–14)
Opioid and psychostimulants 24 7 (4–10)
Opioid and other narcotics 18 5 (3–8)
Opioid and benzodiazepines 16 5 (2–7)
Opioid and antidepressants 14 4 (2–6)
Opioid, cocaine, and other narcotics 13 4 (2–6)
Opioid and alcohol 11 3 (1–5)
Opioid, cocaine, and alcohol 10 3 (1–5)
Opioid, other narcotics, and alcohol 9 3 (1–5)