Table 2.
Estimated marginal means of circulating markers related to liver and pancreas functions in abstinent alcohol use disorders patients and controls.
| Variable | Alcohol with diseases (N = 20) | Alcohol with no diseases (N = 65) | Control (N = 55) | p-Valuea | |
|---|---|---|---|---|---|
| Aspartate transaminase [mean (SD)] | Reference ranges [0.0–40.0] IU/L | 46.11 (4.01)+ | 29.49 (2.24) | 27.94 (3.14) | 0.001 |
| Alanine transaminase [mean (SD)] | Reference ranges [0.0–40.0] IU/L | 49.16 (4.78)++ | 32.34 (2.67) | 30.00 (3.74) | 0.004 |
| Gamma-glutamyltransferase [mean (SD)] | Reference ranges [0.0–45.0] IU/L | 47.84 (7.18)++ | 37.18 (4.00)+++ | 19.48 (5.62) | 0.005 |
| Pancreatic α-amylase [mean (SD)] | Reference ranges [5.0–100.0] IU/L | 77.00 (9.16) | 69.33 (5.11) | 59.84 (7.17) | 0.316 |
| Pancreatic lipase [mean (SD)] | Reference ranges [0.0–67.0] IU/L | 35.42 (3.53) | 39.49 (1.97)+++ | 29.09 (2.76) | 0.011 |
Underlined numbers denote out of reference ranges (normal ranges).
Bold numbers denote significant differences (p < 0.05).
ap-Value from one-way analysis of variance using F statistic.
+,++,+++Significant differences compared to the control group after a multiple post hoc Dunnett/Tukey test.