Fig 3. Effects of pyrethroids on OAT activities.

Activities of OAT1 and OAT3 were determined in OAT-transfected HEK cells in the absence or presence of reference inhibitors or various pyrethroids (each used at 100 μM), as described in Materials and Methods. Data are expressed as percentages of activities found in untreated control cells, arbitrarily set at 100% and indicated by dotted lines on graphs; they are the means ± SEM of three independent assays, each being performed in triplicate. *, p<0.05 when compared to untreated control cells.