Table 1. Properties of LtEc and PEG-LtEc.
Properties | LtEc | PEG-LtEc | |||||
---|---|---|---|---|---|---|---|
P50, mmHg | 26.0 | ± | 1.2 | 25.2 | ± | 1.4 | |
Cooperativity | 2.4 | ± | 0.3 | 1.9 | ± | 0.2† | |
MetHb, % | 4.6 | ± | 1.8 | 4.1 | ± | 1.6 | |
COP, mmHg | 1.0 | ± | 0.2 | 3.8 | ± | 0.3† | |
Viscosity, cP | 1.3 | ± | 0.1 | 1.9 | ± | 0.1 |
Results obtained from three (3) different batches of purification and PEGylation.
†, P<0.05 compared to LtEc