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. 2017 Jan 18;12(1):e0170421. doi: 10.1371/journal.pone.0170421

Table 6. Overall analysis of LAARP vs. PSARP.

Outcomes No. of studies Participants Statistical results Heterogeneity Analysismodel
LAARP PSARP Statistic Value(95%CI) P value I2 (%) P value
Length of hospital stay 3 76 74 WMD -3.08 [-3.83, -2.33] <0.00001 64 0.06 Random
Total postoperative complications 6 120 103 RR 0.66 [0.44, 0.99] 0.05 14 0.33 Fixed
Rectal prolapse 8 164 141 RR 1.23 [0.74, 2.02] 0.42 15 0.31 Fixed
Anal stenosis 5 135 119 RR 1.32 [0.61, 2.86] 0.48 0 0.66 Fixed
Wound infection/dehiscence 4 83 75 RR 0.27 [0.09, 0.85] 0.02 0 0.47 Fixed
Postoperative anorectal manometry
Rectal anal inhibitory reflex 3 57 47 RR 1.07 [0.87, 1.31] 0.53 0 0.39 Fixed
Anal canal resting pressure 3 57 47 WMD 4.10 [0.71, 7.49] 0.02 0 0.47 Fixed
High-pressure zone length 3 57 47 WMD 0.63 [-1.25, 2.52] 0.51 0 0.90 Fixed
Kelly's clinical score
Fecal incontinence 3 57 47 WMD 0.01 [-0.13, 0.14] 0.94 0 0.93 Fixed
Fecal staining 3 57 47 WMD 0.05 [-0.08, 0.18] 0.47 0 0.90 Fixed
Sphincter squeeze 3 57 47 WMD 0.14 [-0.16, 0.44] 0.34 75 0.02 Random
Average score 3 57 47 WMD 0.12 [-0.32, 0.56] 0.58 0 0.80 Fixed
Good ranking 2 24 19 RR 1.50 [0.57, 3.95] 0.42 0 0.42 Fixed
Krickenbeck classification
Voluntary bowel movements 5 71 84 RR 1.18 [0.96, 1.44] 0.11 0 0.78 Fixed
Soiling grade 1 4 47 50 RR 0.78 [0.42, 1.45] 0.44 0 0.49 Fixed
Soiling grade 2 or 3 5 71 84 RR 0.71 [0.39, 1.28] 0.25 0 0.47 Fixed
Grade 1 constipation 2 42 54 RR 0.63 [0.20, 1.93] 0.42 0 0.83 Fixed
Grade 2 or 3 constipation 3 62 73 RR 0.37 [0.14, 0.94] 0.04 23 0.27 Fixed

LAARP, laparoscopically assisted anorectal pull-through; PSARP, posterior sagittal anorectoplasty; WMD: weighted mean difference; RR: risk ratio.