Table 2. Rates of spontaneous unequal SCE in wild type and in mutants defective in RAD52 epistasis-group genes.
his3 substrate | Genotype | Rate of recombination (× 106) | Fold difference in rate, relative to wild type |
---|---|---|---|
his3-SCScontrol | Wild type | 0.76 ± 0.19 | 1 |
his3-SCScontrol | rad50 | 2.63 ± 0.44 | 3.4 ↑ |
his3-SCScontrol | mre11 | 3.40 ± 0.20 | 4.4 ↑ |
his3-SCScontrol | rad51 | 1.36 ± 0.38 | 1.8 ↑ |
his3-SCScontrol | rad52 | 0.16 ± 0.24 | 0.21 ↓ |
his3-SCSCAG71 | Wild type | 1.37 ± 0.15 | 1 |
his3-SCSCAG71 | rad50 | 3.20 ± 0.24 | 2.3 ↑ |
his3-SCSCAG71 | mre11 | 4.12 ± 0.56 | 3.0 ↑ |
his3-SCSCAG71 | rad51 | 1.73 ± 0.31 | 1.3 ↑ |
his3-SCSCAG71 | rad52 | 0.09 ± 0.56 | 0.06 ↓ |
his3-SCSpal140 | Wild type | 9.25 ± 1.67 | 1 |
his3-SCSpal140 | rad50 | 4.67 ± 0.74 | 0.5 ↓ |
his3-SCSpal140 | mre11 | 2.83 ± 0.47 | 0.3 ↓ |
his3-SCSpal140 | rad51 | 2.70 ± 0.20 | 0.29 ↓ |
his3-SCSpal140 | rad52 | 0.58 ± 0.28 | 0.06 ↓ |