Combined effects of karenitecin and flavopridol:
Subconfluent cultures of the T98G cells were treated with the indicated concentrations of flavopridol, or karenitecin, or a combined treatment of both the drugs 72 hours followed by treatment with 5.5 Gy of radiation. Control set of cells was treated with 5.5 Gy radiation, or treated with DMSO alone. The cells were harvested and an optimum number of cells were plated and allowed to grow for 14 days. The resulting colonies were stained and counted. Each graphed point represents mean values ± SE values of triplicate dishes.