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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Pediatr Crit Care Med. 2016 May;17(5):e218–e228. doi: 10.1097/PCC.0000000000000684

Figure 1.

Figure 1

Number of daily and cumulative distinct drug and therapeutic agent exposures in PICU patients by age group. Shown are the levels of exposure to distinct drugs and therapeutic agents for each hospital day, from day 1 up to day 30 of hospitalization in ICU, for patients who remained in ICU for those lengths of stay. For each hospital day, we determined the level of exposure for patients at various percentiles of exposure; the plotted solid lines display the median, the plotted short dash lines display 10th and the 90th percentiles, and the shaded zone the interquartile range (IQR). Number of daily drug exposures is defined as the number of distinct drug and therapeutic agent that patients at each percentile were exposed to on that hospital day in ICU. Number of cumulative drug exposures is defined as the number of distinct drug and therapeutic agent that patients at each percentile were exposed to up to and including that hospital day in ICU.