Table 4.

Differences in average monthly atorvastatin and rosuvastatin expenditures between coupon and non-coupon users.

Time following incident statin fill	Time
	1 month	1 year	2 years	3 years	4 years
Average Copayment, $
No coupons
Predicted level (SE)	19.4 (−0.1)	15.9 (−0.1)	17.0 (−0.1)	16.1 (−0.1)	15.2 (−0.2)
Other coupon
Predicted level (SE)	16.1 (−0.2)	13.0 (−3.0)	13.4 (−6.7)	12.6 (−9.7)	12.1 (−12.6)
Difference from counterfactual*	−3.4 (−0.1)	−2.9 (−3.0)	−3.6 (−6.7)	−3.4 (−9.7)	−3.1 (−12.6)
Initial statin coupon
Predicted level (SE)	16.4 (−1.7)	9.7 (−10.2)	11.0 (−25.8)	14.3 (−51.6)	14.3 (−70.0)
Difference from counterfactual	−2.9 (−1.7)	−5.4 (−10.2)	−6.1 (−25.8)	−2.8 (−51.6)	−2.3 (−70.0)
Subsequent statin coupon
Predicted level (SE)	12.9 (−0.3)	14.7 (−11.0)	15.6 (−25.3)	14.6 (−36.6)	12.2 (−41.6)
Difference from counterfactual	−7.6 (−0.3)	−1.3 (−11.0)	−1.4 (−25.3)	−1.6 (−36.6)	−3.1 (−41.6)
Average Total Cost, $
No coupons
Predicted level (SE)	128.4 (−0.1)	104.6 (−0.2)	112.4 (−0.2)	115.9 (−0.2)	121.4 (−0.4)
Other coupon
Predicted level (SE)	127.3 (−0.3)	106.7 (−6.2)	114.9 (−14.5)	118.2 (−23.0)	121.6 (−32.0)
Difference from counterfactual	−2.5 (−0.3)	1.3 (−6.2)	1.7 (−14.5)	1.9 (−23.0)	0.0 (−32.0)
Initial statin coupon
Predicted level (SE)	143.3 (−1.3)	115.5 (−14.9)	117.3 (−32.7)	121.8 (−52.5)	123.7 (−72.3)
Difference from counterfactual	6.8 (−1.2)	1.4 (−14.9)	−2.6 (−32.7)	0.5 (−52.5)	−1.5 (−72.3)
Subsequent statin coupon
Predicted level (SE)	118.1 (−0.4)	109.6 (−10.1)	115.6 (−23.3)	121.1 (−37.6)	125.1 (−52.5)
Difference from counterfactual	−9.9 (−0.3)	3.6 (−10.1)	1.6 (−23.3)	3.7 (−37.6)	2.6 (−52.5)

^*Difference from counterfactual represents the difference in average predicted values between coupon users and their counterfactual non-coupon using counterparts within each group (initial, subsequent, non-statin)

Source: IMS Health Lifelink LRx Data, 2007–2013