Table 1.

Sleep pattern of wild-type and transgenic rats (n = 8) in 24 h, and separately during the day and the night

	24 h		Day		Night
	WT	TG	WT	TG	WT	TG
Wake
No. of periods	201.33 ± 18.66	192.08 ± 12.21	96.00 ± 11.96	100.42 ± 15.87	106.33 ± 7.86	102.83 ± 9.82
Total time, min	558.18 ± 36.95	590.58 ± 37.18	191.79 ± 16.41	200.16 ± 12.04	366.29 ± 31.26†	388.84 ± 31.65†
%	38.87 ± 2.72	40.12 ± 2.60	26.66 ± 2.3	27.38 ± 1.400	50.91 ± 4.35†	52.86 ± 4.45†
Mean time per stage, s	182.44 ± 30.53	190.71 ± 23.93	133.66 ± 25.59	132.21 ± 20.03	228.24 ± 36.02†	245.5 ± 44.69†
NREM
No. of periods	371.11 ± 24.58	358.83 ± 24.40	211.72 ± 15.24	199.17 ± 13.10	159.61 ± 10.99	160.00 ± 13.64†
Total time, min	782.21 ± 42.61	777.08 ± 34.22	471.33 ± 20.11	479.59 ± 11.54	310.87 ± 26.65†	293.43 ± 27.24†
%	54.31 ± 2.75	53.76 ± 2.28	65.50 ± 2.50	66.05 ± 1.68	43.20 ± 3.70†	41.48 ± 3.71†
Mean time per stage, s	128.22 ± 5.71	132.76 ± 5.84	136.84 ± 7.32	146.51 ± 8.04	117.83 ± 6.07	113.47 ± 4.78†
REM
No. of periods	98.00 ± 15.18	83.50 ± 20.04	56.72 ± 7.10	51.5 ± 14.14	41.83 ± 8.84	31.92 ± 7.21
Total time, min	98.53 ± 13.45	82.96 ± 13.10	56.28 ± 4.78	45.68 ± 6.53	42.37 ± 10.73	36.93 ± 7.86
%	6.82 ± 0.88	6.12 ± 0.95	7.84 ± 0.7	6.57 ± 0.86	5.89 ± 1.49	5.66 ± 1.18
Mean time per stage, s	61.64 ± 3.03	70.31 ± 8.71	62.06 ± 4.17	63.36 ± 9.44	59.85 ± 4.87	79.36 ± 6.32*

Data are presented as means ± SE. WT, wild type; TG, transgenic; NREM, non-rapid eye movement sleep; REM, rapid eye movement sleep. %, Time in a given sleep state (wake, NREM, REM) expressed as a percentage of total period under consideration (24 h; or 12 h for Day and for Night).

^*P < 0.05 vs. WT.

^†P < 0.05 vs. day of the same genotype.