Table 2.
Resting cardiovascular and MSNA measures
| Lean-CON | WM-CON | T2D | P Value | |
|---|---|---|---|---|
| Cardiovascular variables | ||||
| Heart rate, beats/min | 58 ± 3 | 69 ± 1* | 66 ± 2* | 0.004 |
| Systolic BP, mmHg | 114 ± 3 | 118 ± 6 | 125 ± 3 | 0.082 |
| Diastolic BP, mmHg | 73 ± 2 | 79 ± 3 | 78 ± 2 | 0.235 |
| Mean BP, mmHg | 87 ± 2 | 92 ± 4 | 94 ± 2 | 0.167 |
| MSNA | (n = 9) | (n = 9) | (n = 12) | |
| Burst frequency, bursts/min | 22 ± 4 | 25 ± 5 | 29 ± 3 | 0.556 |
| Burst incidence, bursts/100 heartbeats | 39 ± 7 | 37 ± 8 | 44 ± 3 | 0.645 |
| Heart rate variability | ||||
| SDNN, ms | 69 ± 10 | 49 ± 6 | 43 ± 6* | 0.047 |
| RMSSD, ms | 60 ± 14 | 39 ± 9 | 29 ± 5* | 0.041 |
| HF power, ms2 | 1420 ± 677 | 652 ± 259 | 363 ± 114 | 0.110 |
Values are means ± SE.
BP, blood pressure; MSNA, muscle sympathetic nerve activity; SDNN, standard deviation of the normal-to-normal intervals; RMSSD, root-mean-square of successive differences in R-R interval; HF, high frequency.
*
P < 0.05 vs. Lean-CON.