Fig. 8.

Ouabain induced cardiac positive inotropy in vivo. A high-fidelity, 1.4-French Millar Mikro-Tip transducer was advanced into the LV to monitor cardiac performance. The right femoral vein was cannulated for infusion of a bolus of ouabain (0.48 nmol/g body wt) or an equal volume of saline. LV function was recorded throughout drug or saline administration and analyzed off-line. A: dP/dt max; B: dP/dt min (n = 5). Paired t-test was used to compare with baseline and ouabain infusion. *P < 0.05 vs baseline.