Table 1.
Echocardiographic analysis of cardiac size and function in WT and cav-1 KO mice (10–12 wk)
| HR, bpm | LVEDD, mm | LVESD, mm | PWT, mm | SWT, mm | RWT, mm | M-Mode FS, % | B-Mode FS, % | |
|---|---|---|---|---|---|---|---|---|
| WT (n = 13) | 376 ± 21 | 3.3 ± 0.2 | 1.8 ± 0.2 | 1.1 ± 0.1 | 1.0 ± 0.1 | 6.8 ± 0.8 | 47 ± 4 | 52 ± 5 |
| KO (n = 9) | 404 ± 40 | 3.1 ± 0.1 | 1.7 ± 0.1 | 1.2 ± 0.1 | 1.1 ± 0.1 | 7.3 ± 0.6 | 46 ± 3 | 51 ± 4 |
Values are averages ± SE.
WT, wild type; cav-1 KO, caveolin-1 knockout; bpm, beats per min; HR, heart rate; LVEDD, left ventricular end-diastolic internal diameter; LVESD, left ventricular end-systolic internal diameter; PWT, posterior wall thickness; SWT, septal wall thickness; RWT, relative wall thickness; FS, fractional shortening.