Table 3. Subtype/immunohistochemistry of 26 archival NF1 breast cancer tissue samples by age group.
All patients | Age <40 | Age 40–50 | Age >50 | |
---|---|---|---|---|
Patient age | n (%/all) | n (%/age group) | n (%/age group) | n (%/age group) |
n (%/all) | 26 (100%) | 6 (23.1%) | 6 (23.1%) | 14 (53.8%) |
Histological type | ||||
Ductal | 23 (88.5%) | |||
Lobular | 2 (7.7%) | |||
Other | 1 (3.8%) | |||
Breast cancer subtype | ||||
Luminal A | 4 (15.4%) | 0 | 1 (16.7%) | 3 (21.4%) |
Luminal B | 9 (34.6%) | 2 (33.3%) | 4 (66.7%) | 3 (21.4%) |
HER2 subtype | 8 (30.8%) | 3 (50.0%) | 1 (16.7%) | 4 (28.6%) |
Basal-like | 4 (15.4%) | 1 (16.7%) | 0 | 3 (21.4%) |
Triple-negative, other than basal-like | 1 (3.8%) | 0 | 0 | 1 (7.1%) |
Ki-67 | ||||
<20% | 9 (34.6%) | 1 (16.7%) | 3 (50.0%) | 5 (35.7%) |
>20% | 17 (65.4%) | 5 (83.3%) | 3 (50.0%) | 9 (64.3%) |
Grade | ||||
I | 1 (3.8%) | 0 | 0 | 1 (7.1%) |
II | 11 (42.3%) | 2 (33.3%) | 4 (66.7%) | 5 (35.7%) |
III | 14 (53.8%) | 4 (66.7%) | 2 (33.3%) | 8 (57.1%) |
Abbreviations: HER2=human epidermal growth factor receptor 2; NF1=neurofibromatosis 1.