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. 2016 Dec 8;116(2):211–217. doi: 10.1038/bjc.2016.403

Table 3. Subtype/immunohistochemistry of 26 archival NF1 breast cancer tissue samples by age group.

  All patients Age <40 Age 40–50 Age >50
Patient age n (%/all) n (%/age group) n (%/age group) n (%/age group)
n (%/all) 26 (100%) 6 (23.1%) 6 (23.1%) 14 (53.8%)
Histological type        
 Ductal 23 (88.5%)      
 Lobular 2 (7.7%)      
 Other 1 (3.8%)      
Breast cancer subtype        
 Luminal A 4 (15.4%) 0 1 (16.7%) 3 (21.4%)
 Luminal B 9 (34.6%) 2 (33.3%) 4 (66.7%) 3 (21.4%)
HER2 subtype 8 (30.8%) 3 (50.0%) 1 (16.7%) 4 (28.6%)
 Basal-like 4 (15.4%) 1 (16.7%) 0 3 (21.4%)
 Triple-negative, other than basal-like 1 (3.8%) 0 0 1 (7.1%)
Ki-67        
 <20% 9 (34.6%) 1 (16.7%) 3 (50.0%) 5 (35.7%)
 >20% 17 (65.4%) 5 (83.3%) 3 (50.0%) 9 (64.3%)
Grade        
 I 1 (3.8%) 0 0 1 (7.1%)
 II 11 (42.3%) 2 (33.3%) 4 (66.7%) 5 (35.7%)
 III 14 (53.8%) 4 (66.7%) 2 (33.3%) 8 (57.1%)

Abbreviations: HER2=human epidermal growth factor receptor 2; NF1=neurofibromatosis 1.