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. 2016 Dec 13;116(2):202–210. doi: 10.1038/bjc.2016.411

Table 2. Frequencies of analysed end points by the CBMN assay in peripheral blood mononuclear cells of BC cases and healthy controls.

 
  Controls All BC Cases Pb NMIBC Pb MIBC Pb
Frequenciesa N 148 152   136   16  
MN Mean±s.d. 7.73±3.91 9.51±4.73 0.001 9.68±4.77 0.0005 8.06±4.24 0.91
NPB Mean±s.d. 0.88±0.90 0.98±1.03 0.61 0.99±1.03 0.55 0.88±1.09 0.85
NBUD Mean±s.d. 3.99±2.44 5.06±3.36 0.006 5.20±3.41 0.002 3.87±2.69 0.65

Abbreviations: BC=bladder cancer; MIBC=muscle-invasive bladder cancer; MN=micronuclei; NBUD=nuclear buds; NMIBC=non-muscle invasive bladder cancer; NPB=nucleoplasmic bridge.

Significant results in bold.

a

Mean frequencies for 1000 binucleated cells.

b

Wilcoxon Rank sum test.