Table 7.
Characterization of Motif Distribution in Compartments
| Coveragea | Average number of motifs per covered protein | Proteins predicted on by PSLT using >1 motif | Motif frequencyb | Motif compartment specificity indexc | |
|---|---|---|---|---|---|
| ER | 83.6% | 2.0 | 56% | 2.3 | 0.49 |
| Golgi | 75.0% | 1.7 | 26% | 1.7 | 0.59 |
| Cytosol | 89.4% | 2.2 | 59% | 1.8 | 0.43 |
| Nucleus | 93.2% | 2.3 | 66% | 3.4 | 0.24 |
| Peroxisome | 86.4% | 2.1 | 55% | 1.3 | 0.67 |
| Plasma membrane | 94.1% | 3.4 | 80% | 3.6 | 0.47 |
| Lysosome | 86.8% | 1.4 | 25% | 1.5 | 0.49 |
| Mitochondria | 80.6% | 1.9 | 48% | 1.5 | 0.40 |
| Extracellular | 90.1% | 1.9 | 47% | 2.5 | 0.34 |
a
The coverage represents the percentage of human proteins in a given compartment that contain at least one InterPro motif.
b
The motif frequency is calculated as the total number of motifs in all proteins in a given compartment divided by the number of distinct motifs found in proteins in that compartment.
c
The motif compartment specificity index is calculated as the number of distinct motifs that are unique to a given compartment divided by the total number of distinct motifs in that compartment.