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. 2017 Jan 18;91(3):e01443-16. doi: 10.1128/JVI.01443-16

TABLE 1.

Amino acids that form structurally consistent core regionsa

Complex Positions
PVSP17B PVSS12B PVSS10E PVSS7A
VHH, all ordered 1–124 1–123 1–124 1–125
VHH coreb 1–12 1–12 6–21 2–96
15–31 17–31 25–27
34–97 34–97 39–52
57–70
72–97
112–120 112–120 113–122
VP1, all ordered 57–213 57–213 71–212 71–213
232–279 232–279 232–279 232–279
VP1 core 72–94 72–94 72–94 73–93
107–155 107–155 107–155 107–157
172–174 172–174 172–174
177–180 177–180 177–180
183–209 183–209 183–209 183–213
240–267 240–267 240–267 240–267
272–279 272–279 272–279
VP2, all ordered 1–43 1–43 1–42 10–43
53–159 53–159 55–159 53–159
174–269 174–269 175–268 175–268
VP2 core 30–43 30–43 30–42 30–43
53–100 53–100 55–100 53–132
102–133 102–133 102–132
143–159 143–159 144–159 143–159
175–238 175–238 175–238 195–239
250–259 250–259 250–259 247–260
VP3, all ordered 1–231 1–231 1–230 1–175
185–230
VP3 core 1–12c 1–12c 1–12c 1–12c
13–43c 13–43c 13–43c 13–43c
44–70 44–70 44–70 44–71
83–87 83–87 83–87
95–121 95–121 95–121
126–133 126–133 130–133 82–135
142–177 142–177 142–172 143–147
190–201 190–201 192–193 155–156
206–225 206–225 206–225 188–226
a

Residues that were restrained to agree with main-chain coordinates from the structural homolog.

b

The amino acid residues correspond to the sequence of the antipoliovirus VHH.

c

N-terminal residues of VP3 are piecewise rigid bodies.