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Addition of digoxin or digitoxin inhibits redistribution of host SR proteins in infected cells. A549 cells were either uninfected or infected with HAdVC5 and treated with DMSO, digitoxin (100 nM), or digoxin (100 nM) immediately after removal of the virus inoculum. Cells were fixed at 24 h p.i. and stained for DNA (DAPI) or for Tra2β. Images were taken using a 63× oil objective. Shown are representative images from three independent experiments.
