FIG 8.
Negative effect of GPI-scFv X5-transduced CD4 T cells on viral replication in lymphoid tissues. Shown are normalized HIV-1 DNA (A and B) and RNA (C and D) copy numbers in spleen and bone marrow. HIV-1 DNA or RNA copy numbers were divided by CD3+ CD8− cell counts. (A and C) Data from mice infected with JR-CSF. (B and D) Data from mice infected with BK132. Spleen and bone marrow cells were collected on the day of euthanasia. Due to very low cell recovery, the result for one mouse in the X5/X4 group was excluded. Mean values for each group are shown.