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. 2017 Jan 19;7:40859. doi: 10.1038/srep40859

Figure 1. CCT inhibits α-syn A53T fibrillation.

Figure 1

(a) Fibrillation kinetics of α-syn A53T in the presence of ATP or ADP and increasing molar ratios of CCT or GroEL, measured by ThT fluorescence. Chaperonins without α-syn A53T were used as controls. Fluorescence data is normalized as a percentage of maximum fluorescence. Bars show mean ± SD, n = 3–8. For GroEL, one representative experiment is shown. (b) TEM images of the final point of fibrillation kinetics for α-syn A53T, alone or with CCT and ADP.