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. 2017 Jan 19;7:40859. doi: 10.1038/srep40859

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(a) CCT binding to α-syn A53T monomers. SEC profile of CCT, α-syn A53T and the mixture of both. Inset: SDS-PAGE of the fractions corresponding to the CCT peak (black line in SEC profile) of the α-syn A53T + CCT sample. CCT subunit band, green arrow. No α-syn A53T band is visible in the gel, which should appear near the 15 kDa position (red arrow) (see Fig. 4a). (b) CCT binding to fibres assayed by ultracentrifugation. Percentage of CCT, CCT with ADP-AlF₃ or GroEL that coprecipitate with fibres. The percentage of CCT or GroEL precipitated in the absence of fibres is shown as a control.