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. 2017 Jan 19;7:40729. doi: 10.1038/srep40729

Table 3. KRAS signature in EAC.

  Genes References
Upregulated (85) SPINK1, MMP1, TSPAN1, RBP4, CCL20, IL8, TOX3, PLAUR, INHBA, TMEM176B, HSD17B2, ANO1, STC1, FBP1, BIRC3, DENND5B, TNFAIP3, IGFBP3, TFPI, PTGS2, CXCL1, ID2, PTPRR, MMP9, ETS1, MMP15, GLRX, A2M, MMP10, TBX3, RNASE1, CXCL2, TNFSF15, ETV4, IL1B, BMP2, DDIT3, SCG5, ESM1, NR1H4, SEMA3B, MSMB, HAS2, GPR4, PIWIL1, ADAM8, G0S2, NRCAM, SPRY2, LPL, PRRX1, PLVAP, ADAMTS6, SEMA3A, CXCL5, PPP1R14D, DOCK4, GPR124, SPP1, ANPEP, USH1C, TGM2, MMP11, SYT1, UGT8, MMD, FABP3, MLXIPL, MGAT4A, ETV5, NRP1, TLR4, FMNL2, SCN2A, PELI2, LRCH1, ITGBL1, TRIB2, SOX9, CD80, CXCR4, DNAJA4, ZEB1, DUSP4, PLAT http://software.broadinstitute.org/gsea/msigdb/cards/KRAS.600.LUNG.BREAST_UP.V1_UPhttp://software.broadinstitute.org/gsea/msigdb/cards/KRAS.LUNG.BREAST_UP.V1_UPhttp://software.broadinstitute.org/gsea/msigdb/cards/KRAS.600_UP.V1_UP
Downregulated (114) CALML5, SH3GL3, CXCL14, AKAP6, MC5R, PLCH2, TRIM48, IGFBP2, VAV3, DEFB1, TF, GPNMB, MAFB, CALML3, S100A7, EPHB3, SLC6A9, KLK7, KRT16, SPTBN2, CRYAB, AKR1B10, UPK3B, KRT1, CYP2C18, SCGB1A1, SLC39A2, ACPP, BBOX1, LY6D, KLK12, KLK11, CRABP2, IVL, CYP4B1, LYPD3, FMO2, S100A12, ALDH3B2, SPRR3, KRT4, KRT13, TGM1, KRT15, ZNF750, RHCG, SERPINB3, SERPINB13, CLCA4, EPHX2, NOS1, RRAD, EPHB6, SPRR1B, PRODH, PLEKHH3, DLK2, BCL11B, HRASLS, FCGBP, ABCG4, IL19, DPT, EDN2, CYP2C19, MAML3, RASAL1, THBD, SLC30A4, CAMK1D, IMPA2, YOD1, PRRG4, CLDN8, FGFR3, BLNK, FETUB, KRT31, CD207, CLIC3, KLF8, HSPB8, DSG1, SPRR1A, DSG3, CLCA2, SIDT1, DTX2, FMO6P, HCN2, METTL7A, ALOX12B, GABRA4, BDKRB1, EPB41L4A, DENND2D, PLAC8, FAM189A2, SLC25A23, CACNA2D3, IL12A, PVRL1, EPHX3, SERPINB7, CD96, MUC4, ADAM23, PI3, ITGB7, RASGRP1, TFAP2B, CLDN17, S100A8, SCEL http://software.broadinstitute.org/gsea/msigdb/cards/KRAS.LUNG_UP.V1_DNhttp://software.broadinstitute.org/gsea/msigdb/cards/KRAS.600_UP.V1_DNhttp://software.broadinstitute.org/gsea/msigdb/cards/KRAS.300_UP.V1_DNhttp://software.broadinstitute.org/gsea/msigdb/cards/KRAS.LUNG.BREAST_UP.V1_DNhttp://software.broadinstitute.org/gsea/msigdb/cards/KRAS.600.LUNG.BREAST_UP.V1_DNhttp://software.broadinstitute.org/gsea/msigdb/cards/KRAS.PROSTATE_UP.V1_DN