Table 3. Restoration of marker genes levels and glutamate release after cocktail treatment.
| Hip | Cll | IC | SC | Ctx | |
|---|---|---|---|---|---|
| Ho1 | 164.26b | 90.20 | 101.92 | 110.61 | 100.94 |
| Srnx1 | 106.6 | 61.58 | 51.96 | 45.65 | 31.84 |
| Tnfα | 33.72 | 91.05 | 91.46 | 32.12c | 62.61 |
| Il1β | 4.42b | 27.01 | 4.26b | 6.99b | 20.84 |
| Il6 | 17.67b | 11.09b | 7.62b | 1.16 | 7.65b |
| Cox2 | 2.60a | 4.91b | 2.25b | 71.99 | 40.00 |
| Glu | 58.53b | 94.52 | 66.14a | 98.04 | 116.14 |
The expression of selected genes/glutamate release was expressed as % of gene expression compared with the same sample challenged with bilirubin. Ho1: heme oxygenase1; Srxn1: sulfiredoxin 1; Tnfα: tumor necrosis factor alfa; Il1β: interleukin 1β; Cox2: cyclo-oxygenase 2; Glu: glutamate. Data are expressed as the means of three-five biological repetitions. Statistical relevance: ap < 0.05; bp < 0.01; cp < 0.001. Hip: hippocampus; Cll: cerebellum; IC: inferior colliculus; SC: superior colliculus; Ctx: cortex.