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. 2017 Jan 19;7:41042. doi: 10.1038/srep41042

Table 1. Demographics and medical treatment in the two MDS patients.

  Sex (M/F) Age at surgery (years) Age at onset (yeas) DYT1 DYT11 Predominant complaints on admission Myoclonus distribution Dystonia distribution Alcohol sensitivity DBS Previous medical treatment Follow up (months)
P1 M 30 12 c.904_906delGAG, p.Glu303del(exon5) c.1294 A > C, p.Ser432Arg (exon10) myoclonus neck, trunk, UL, LL voice, neck, trunk, UL, LL + Vim, GPi* trihexyphenidyl, selegiline, clonazepam 54
P2 M 17 11 c.904_906delGAG, p.Glu303del(exon5) c.1294 A > C, p.Ser432Arg (exon10) hand dystonia UL, LL voice, UL, LL Not test Vim clonazepam 6

MDS: myoclonus dystonia syndrome, M/F: Male/Female, DYT1: Torsin A gene mutation, DYT11: SGCE gene mutation, +: positive, −: negative, GPi: globus pallidus internus, Vim: ventral intermediate thalamic nucleus, UL: upper limb, LL: lower limb. *Initial bilateral Vim DBS was performed and subsequent bilateral GPi DBS was offered at 43 months after initial surgery.