Table 2.
SD change in cIMT per 1 SD change in exposure (95% CI) (n = 3366) | ||||||
---|---|---|---|---|---|---|
Exposure | Model 1 | p Value | Model 2 | p Value | Model 3 | p Value |
Total hip BMD | 0.068 (0.034, 0.102) | <0.001 | 0.110 (0.077, 0.144) | <0.001 | 0.063 (0.025, 0.101) | 0.001 |
Femoral neck BMD | 0.057 (0.022, 0.091) | 0.001 | 0.105 (0.071, 0.139) | <0.001 | 0.055 (0.018, 0.091) | 0.004 |
Trochanter BMD | 0.089 (0.055, 0.122) | <0.001 | 0.116 (0.083, 0.150) | <0.001 | 0.069 (0.032, 0.106) | <0.001 |
CSMI | 0.106 (0.072, 0.140) | <0.001 | 0.118 (0.085, 0.151) | <0.001 | 0.052 (0.012, 0.092) | 0.011 |
Total body BMD | 0.084 (0.051, 0.119) | <0.001 | 0.132 (0.099, 0.165) | <0.001 | 0.071 (0.030, 0.112) | 0.001 |
Total body BA | 0.087 (0.053, 0.121) | <0.001 | 0.117 (0.084, 0.151) | <0.001 | 0.048 (–0.004, 0.100) | 0.071 |
Total body BMC | 0.097 (0.063, 0.131) | <0.001 | 0.139 (0.105, 0.172) | <0.001 | 0.076 (0.027, 0.125) | 0.003 |
aBMC | 0.124 (0.031, 0.217) | 0.009 | 0.218 (0.128, 0.309) | <0.001 | 0.152 (0.051, 0.253) | 0.003 |
cIMT = common carotid intima‐media thickness; CI = confidence interval; BMD = bone mineral density; CSMI = cross‐sectional moment of inertia (cm4); BA = bone area; BMC = bone mineral content; aBMC = area‐adjusted total body bone mineral content.
Table shows results of linear regression analysis between hip and total body DXA measurements and cIMT in 3366 individuals. Results are standard deviation change in cIMT per standard deviation increase in exposure (95% confidence intervals) and p value. Model 1 = unadjusted analysis; model 2 = adjustment for age; model 3 = model 2 plus additional adjustment for height, lean mass, fat mass, menopause, smoking, hormone replacement, calcium and/or vitamin D supplement use, and education.