Table 5.

The Association Between Hip and Total Body DXA Measurements and cIMT Among ALSPAC Study Adolescents

	SD change in cIMT per 1 SD change in exposure (95% CI) in males and females combined (n = 4368)
Exposure	Model 1	p Value	Model 2	p Value	Model 3	p Value
Total hip BMD	0.166 (0.137, 0.196)	<0.001	0.124 (0.092, 0.156)	<0.001	0.072 (0.035, 0.110)	<0.001
Total hip BMC	0.199 (0.170, 0.229)	<0.001	0.178 (0.137, 0.220)	<0.001	0.089 (0.031, 0.147)	0.003
Femoral neck BMD	0.152 (0.123, 0.182)	<0.001	0.116 (0.085, 0.147)	<0.001	0.067 (0.031, 0.102)	<0.001
Trochanter BMD	0.170 (0.140, 0.199)	<0.001	0.128 (0.096, 0.160)	<0.001	0.080 (0.043, 0.117)	<0.001
CSMI	0.164 (0.135, 0.193)	<0.001	0.108 (0.067, 0.148)	<0.001	–0.013 (–0.066,0.040)	0.622
Total body BMD	0.177 (0.147, 0.206)	<0.001	0.131 (0.097, 0.166)	<0.001	0.072 (0.025, 0.118)	0.002
Total body BA	0.180 (0.150, 0.209)	<0.001	0.112 (0.078, 0.145)	<0.001	0.104 (0.042, 0.165)	0.001
Total body BMC	0.161 (0.131, 0.190)	<0.001	0.135 (0.100, 0.169)	<0.001	0.115 (0.055, 0.175)	<0.001
aBMC	0.276 (0.181, 0.370)	<0.001	0.213 (0.115, 0.311)	<0.001	0.102 (–0.010, 0.214)	0.074

cIMT = common carotid intima‐media thickness; CI = confidence interval; BMD = bone mineral density; BMC = bone mineral content; CSMI = cross‐sectional moment of inertia (cm⁴).

Table shows results of linear regression analysis between hip DXA measurements and cIMT in 4368 individuals. Results are standard deviation change in cIMT per standard deviation increase in exposure (95% confidence intervals) and p value. Model 1 = unadjusted analysis; model 2 = adjustment for age and sex; model 3 = model 2 plus additional adjustment for height and lean and fat mass.