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. 2017 Jan 19;18:4. doi: 10.1186/s13059-016-1137-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Coagulation associated mRNAs accumulate in the blood of EBOV-infected patients. Box and whisker plots illustrate the expression of the top acute phase genes that are differentially expressed between controls (blue), fatal (red), and survivors (green) based on log2 fold change. From left to right, the graphs illustrate mRNA expression for albumin (ALB), fibrinogen alpha (FGA), fibrinogen beta (FGB), fibrinogen gamma (FGG) and fibrinogen gamma-like 1 (FGL1). Black brackets indicate significance between control and survivor or fatal levels and grey brackets indicate significance level between survivors and those who will succumb to disease. All brackets represent a log2(fold change) > 2 and FDR < 5 %