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. 2004 Oct 18;101(43):15370–15375. doi: 10.1073/pnas.0406499101

Fig. 4.

Fig. 4.

Colocalization of phophorylated Akt with 14-3-3ζ in ISCs. (a) The crypt-villus of intestine from BMP receptor type 1A knockout mouse were stained with antiphosphorylated Akt-specific (red) (Upper Left) or anti-14-3-3ζ-specific (green) (Upper Right) antibodies. Counterstaining with 4′,6-diamidino-2-phenylindole reveals the cell nuclei (blue). (b) A model for the stabilization mechanism of β-catenin by Akt and 14-3-3ζ.